Testosterone: Signs and Symptoms of low and high testosterone, laboratory testing of Testosterone

 Testosterone

Testosterone is main male sex hormone. In males (Human) testosterone plays a very important role or we can say key role in development of male reproductive tissues such as testes and prostate as well as helping in promoting secondary sexual  characteristics such as increased muscle and bone mass, and the growth of body hair. Testosterone is most often associated with sex derive, and plays a vital role in sperm production. The way men store fat in the body, and even red blood cell production. A men testosterone levels can also affect his mood.




Testosterone is a hormone found in humans, as well as in other animals
  • Testicles primarily make testosterone in men 
  • Women's ovaries also make testosterone, in very small amount

Chemistry of testosterone

Testosterone is a potent steroid hormone whose chemical formulation is C19-H28-O2. Testosterone is also known as 17-beta-hydroxy-4-androstene-3-one.

How testosterone produces

  • The hypothalamus is decision maker. It puts request for how testosterone should be produced 
  • The pituitary gland takes orders from the hypothalamus and passes instructions to the testicles 
  • Hypothalamus makes gonadotropin releasing hormone (GnRH), which controls the release of other hormones from pituitary gland 
  • Luteinizing hormone (LH) and follicle stimulating hormone (FSH) are the two important messenger hormones that pituitary gland makes, which then act on your testicles to make testosterone and sprem.
  • The adrenal glands located above the kidneys, make a hormones, including a small amount of testosterone. 
  • Testosterone is produced mainly in testicles. 
  • Sperm production is very ending job that requires a steady supply of testosterone
  • Testosterone surges during adolescence to help the testicles and panis mature.
  • Throughout a man's life, testosterone affects his level of sexual desire.

Role of testosterone in human male 

Many people know that testosterone is important for man's sexual desires, yet testosterone has numerous other important functions through our the body 
  • Testosterone is very important for strong bones 
  • Testosterone also causes men to have higher red blood cells count then women
  • After puberty, testosterone in men causes them to develop more muscle mass and less body fat compared with women 
  • Testosterone is important for the physical changes that happen during puberty, such as the development of penis, testicles, facial and body hair. 
  • Testosterone acts on cells in testicles to make sperm 
  • Testosterone effects mood and sex drive. 
  • Testosterone help in man to regulate pain levels means pain tolerance capacity
  • Testosterone aid in learning and memory, especially especially spatial intelligence.

Disease and Disorders that affects Testosterone levels 

When testosterone levels are abnormally low or high, it overall effects the health and well-being of an individual

In man, possible causes if low testosterone include
  • Age (after 50)
  • Smoking 
  • Overweight 
  • Under weight 
  • Congenital or chromosomal disease 
  • Disease involveing the testicles
  • Problem in pituitary gland 
  • Abnormally high levels of irons 
  • Major illness or surgery
  • Chemotherapy and other cancer treatment
  • Some medication and recreational drugs 
  • Extremely high level of stress 

Signs of low testosterone

If a man develop low testosterone, certain signs or symptoms may appear, such as 
  • Low sexual drive 
  • Erectile problems 
  • Fewer morning erections 
  • Less facial hair 
  • Osteoporosis
  • Decreased strength 
  • Depression and depressed mood 
  • Tiredness
  • Problem with sleep 
  • Irritability
  • Decreased interest in activities 

Signs of high Testosterone

Men with high testosterone can experience a variety of troubling symptoms and possible health consequences
  • Excess testosterone can lead to more aggressive and irritable behaviour
  • More acne and oily skin
  • Increase in muscle mass 
  • With to much testosterone pumping through your system, you may have lower sperm count and shrunken testicles. 
  • Excess testosterone in can causes testicular or adrenal tumors 
  • Elevated levels testosterone will raise bad cholesterol levels and can leads to heart heath issues. 
  • Man with high level of testosterone actually have genetic predisposition. These individuals that falls with in this category are at a much higher risk of developing blood clots, heart disease, and a variety of other cardiovascular issues. 

Laboratory testing of Testosterone

A simple blood test can determine testosterone levels. There wide range of normal or healthy levels of testosterone circulating in the bloodstream

The normal range of testosterone for man is between 280 and 1,100 nanograms per deciliter (ng/dL) for adult males

Between 15 and 70 ng/dL for adult female

If an adult male's testosterone levels are below 300 ng/dL. Ask your doctor to work up to determine the cause of low testosterone.
Testosterone therapy is available to treat man low levels of testosterone. 


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